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Current status of the chemiosmotic hypothesis

The redox complexes of the mitochondrial chain

• NADH:ubiquinone oxidoreductase,- Complex I
• Succinate:ubiquinone oxidoreductase,- Complex II
• Ubiquinol:cyt c oxidoreductase, Cytochrome bc₁-complex,- Complex III
• Cytochrome oxidase,- Complex IV

Chime

A Table showing membrane proteins for which crystallographic structures are curently available (from Martmut Michel's lab)

The ATP synthase enzyme

• ATP synthase,- see Lecture 10

Chemiosmotic coupling between electron transport and ATP synthesis

• Physical chemistry of transport; transport of protons
• Comparison of electrochemical cell and protochemical cell
• Generalized proton circuit, with stoichiometries for mitochondria, chloroplasts and photosynthetic bacteria
• Peter Mitchell and the chemiosmotic hypothesis